Friday, July 16, 2010
Saturday, July 10, 2010
Antibody can cuts brain damage by 70pc in strokes
London, July 10: Scientists have developed an antibody that could reduce the side effects of a common stroke drug.
The traditional treatment for ischaemic stroke, in which a blood clot cuts off the blood supply to brain tissue, is a drug called rtPA, which dissolves the clot. However, people with haemorrhagic stroke, in which a blood vessel in the brain bursts, should not receive rtPA as it increases the risk of bleeding.Now a new discovery by Denis Vivien of the University of Caen Basse-Normandie in France has put a different perspective on this relatively simple picture: rtPA is actually released by brain cells, reports New Scientist.
In small quantities, rtPA binds to brain-cell receptors for a chemical called NMDA. This triggers a short-lived influx of calcium, enhancing learning and memory.
But damaged neurons release rtPA in large quantities, and this can cause neighbouring neurons to die. High levels of rtPA can also damage the blood-brain barrier, which may explain why the drug sometimes triggers dangerous bleeding. Vivien has also developed an antibody that could overcome these problems.
It stops rtPA from binding to the NMDA receptors, blocking its negative effects.When mice were injected with the antibody on its own or in combination with rtPA, the amount of brain damage resulting from a stroke was reduced by up to 70 per cent - both when the antibody was given immediately after the stroke and 6 hours later. Three months later, these mice also showed significantly less disability.
“With the antibody, we completely prevent the deleterious effect of rtPA and we can increase the time window during which it can be given,” New Scientist quoted Vivien as saying.Source
The traditional treatment for ischaemic stroke, in which a blood clot cuts off the blood supply to brain tissue, is a drug called rtPA, which dissolves the clot. However, people with haemorrhagic stroke, in which a blood vessel in the brain bursts, should not receive rtPA as it increases the risk of bleeding.Now a new discovery by Denis Vivien of the University of Caen Basse-Normandie in France has put a different perspective on this relatively simple picture: rtPA is actually released by brain cells, reports New Scientist.
In small quantities, rtPA binds to brain-cell receptors for a chemical called NMDA. This triggers a short-lived influx of calcium, enhancing learning and memory.
But damaged neurons release rtPA in large quantities, and this can cause neighbouring neurons to die. High levels of rtPA can also damage the blood-brain barrier, which may explain why the drug sometimes triggers dangerous bleeding. Vivien has also developed an antibody that could overcome these problems.
It stops rtPA from binding to the NMDA receptors, blocking its negative effects.When mice were injected with the antibody on its own or in combination with rtPA, the amount of brain damage resulting from a stroke was reduced by up to 70 per cent - both when the antibody was given immediately after the stroke and 6 hours later. Three months later, these mice also showed significantly less disability.
“With the antibody, we completely prevent the deleterious effect of rtPA and we can increase the time window during which it can be given,” New Scientist quoted Vivien as saying.Source
Online sex shops booming in China
July 10 : More and more Chinese are going online to buy sex toys and products these days.
“Many Chinese want to buy sex toys but cringe at the thought of entering sex shops,” Li Yinhe, a sociologist and sexologist with the Chinese Academy of Social Sciences, said.
“Online sex-toy shopping can avoid such problems since consumers don’t have to reveal their real names,” Yinhe added.Taobao.com, China’s largest online shopping destination has about 4,500 sex shops registered and raked in about 60 million yuan in transactions of adult products in June, reports the China Daily.
“Sex toys, especially blow-up dolls which cost a store 10,000 yuan, can sell for 40,000 yuan,” said Tao Ran, the public relations manager of taobao.com said.Moreover, customers can find ‘better’ sex toys and products online than they find in stores. But some still prefer the conventional way.
“I never shop online, especially for something like adult toys, because I don’t think all the products would pass quality control,” said a consumer at a sex shop in Sanlitun, one of Beijing’s busiest areas.
“Many Chinese want to buy sex toys but cringe at the thought of entering sex shops,” Li Yinhe, a sociologist and sexologist with the Chinese Academy of Social Sciences, said.
“Online sex-toy shopping can avoid such problems since consumers don’t have to reveal their real names,” Yinhe added.Taobao.com, China’s largest online shopping destination has about 4,500 sex shops registered and raked in about 60 million yuan in transactions of adult products in June, reports the China Daily.
“Sex toys, especially blow-up dolls which cost a store 10,000 yuan, can sell for 40,000 yuan,” said Tao Ran, the public relations manager of taobao.com said.Moreover, customers can find ‘better’ sex toys and products online than they find in stores. But some still prefer the conventional way.
“I never shop online, especially for something like adult toys, because I don’t think all the products would pass quality control,” said a consumer at a sex shop in Sanlitun, one of Beijing’s busiest areas.
WestLife' Soledad Lyrics
Free MP3 Downloads at MP3-Codes.com
Westlife - Soledad -
If only you could see the tears
In the world you left behind
If only you could heal my heart
Just one more time
Even when I close my eyes
There's an image of your face
And once again I come to realize
You're a loss I can't replace
Soledad, it's a keeping for the lonely
Since the day that you were gone
Why did you leave me, Soledad?
In my heart you were the only
And your memory lives on
Why did you leave me, Soledad?
Walking down the streets of Nothingville
Where our love was young and free
Can't believe just why an empty place
It has come to be
I would give my life away
If it could only be the same
'Cause I can't still the voice inside of me
That is calling out your name
Soledad, it's a keeping for the lonely
Since the day that you were gone
Why did you leave me, Soledad?
In my heart you were the only
And your memory lives on
Why did you leave me, Soledad?
Time will never change
The things you've told me
After all we're meant to be
Love will bring us back to you and me
If only you could see
Soledad, it's a keeping for the lonely
Since the day that you were gone
Why did you leave me, Soledad?
In my heart you were the only
And your memory lives on
Why did you leave me, Soledad?
It's a keeping for the lonely
Since the day that you were gone
Why did you leave me, Soledad?
In my heart you were the only
And your memory lives on
Why did you leave me, Soledad?
Why did you leave me, Soledad?
WestLife' Tonight Lyrics
Westlife is an Irish pop group formed on 3 July 1998. The group's original lineup comprised Nicky Byrne, Kian Egan, Mark Feehily, Shane Filan and Brian McFadden (departed from the band in 2004). The group is the only act in UK history to have their first seven singles go straight to Number 1, and they have gone on to sell over 44 million records worldwide[1] which includes their studio, single, video, and compilation albums.Despite the group's worldwide success, they've only had one U.S. hit on the Billboard Hot 100 charts: "Swear It Again," which made it to #20 in 2000.Westlife were originally signed by Simon Cowell and are currently managed by Louis Walsh. In 2008, they were declared as Ireland's ninth-richest celebrities under 30 years old and 13th in general with 36 million euros as a group. In 2009, they dropped as 16th richest Irish with estimated 8 million euros each. They garnered 14 number one singles in the United Kingdom, the third-highest in UK history, tying with Cliff Richard and trailing behind only Elvis Presley and The Beatles. The group has also broken a few top records, including "Music artist with most consecutive number 1's in the UK". It was officially announced by the Official Charts Company that they are the "2nd biggest selling artist" (trailing behind Robbie Williams) and "Biggest selling band of the decade" (beating Coldplay) in UK with 11 million album sales.At the same time, their very own song "Evergreen" was hailed as the top selling single in the UK of the decade (2000-2010). (See Westlife records)
Over years of their career, Westlife's music has evolved from teen pop to a pop sound, with an emphasis on ballads. Most of the group's hits have been composed by experienced songwriters, most notably Steve Mac and Wayne Hector. (See Songs written)
On 1 June 2008, Westlife marked their 10th anniversary with a concert in Croke Park, Dublin which saw more than 83,000 fans attending the special occasion. Music Week revealed on their website that Westlife is the official third top touring act within the years 2005–2008, while they were 7th top touring act of 2008.
Free MP3 Downloads at MP3-Codes.com
Tonight - Westlife
Lately I'm so tired, if I took it all I'll warn you
I never meant to, if I left you outside
If you ever felt I'd ignored you
No my life is all you
So put your best dress on
And wrap yourself in the arms of someone
Who wants to give you all the love you want
Tonight, I'm gonna make it up to you
Tonight, I'm gonna make love to you
Tonight, you're gonna know how much I missed you, baby
Tonight, I dedicate my heart to you
Tonight, I'm gonna be a part of you
Tonight, you're gonna know how much I miss you
And I miss you so
I don't wanna act like
I know that you'd be mine forever
Though I hope it's forever
Don't want you to feel like
I take you for granted
Whenever we are together
So put your best dress on
And wrap yourself in the arms of someone
Who wants to give you all the love you want
Tonight, I'm gonna make it up to you
Tonight, I'm gonna make love to you
Tonight, you're gonna know how much I miss you, baby
Tonight, I dedicate my heart to you
Tonight, I'm gonna be a part of you
Tonight, you're gonna know how much I miss you
And I miss you so
Oh yeah, so put your best dress on
Wrap yourself in my arms of my love
Tonight, I'm gonna make it up to you
Tonight, I'm gonna make love to you
Tonight, you're gonna know how much I miss you, baby
Tonight, I dedicate my heart to you
Tonight, I'm gonna be a part of you
Tonight, you're gonna know how much I miss you, baby
Tonight, I'm gonna make it up to you
Tonight, I'm gonna make love to you
Tonight, you're gonna know how much I miss you, baby
Tonight, I dedicate my heart to you
Tonight, I'm gonna be a part of you
Tonight, you're gonna know how much I miss you
And I miss you so
Keep Young' With Instant Anti Ageing Creams
How would you like to look young once again, especially before that college reunion? Slap on some instant anti-ageing cream and watch the difference - of course, not without consulting the experts.These products have become a rage with celebrities and commoners alike as they produce ‘just-before-the-party’ results like instant skin lifting, tightening and firming for visible reduction of lines and wrinkles sans any stiffening.
Also known as third generation products, they also help in instant lip enhancement or augmentation for fuller and luscious lips. In India, the best known range is available under the American brand Clinicians Complex.
“These creams have become very popular and people are willing to spend on these products because they give instant result,” Sanjay Parasar, a leading plastic, aesthetic and craniofacial surgeon and laser specialist, told IANS.
“For instance, there is an instant tightening serum, which is ideal before special occasions and it immediately diminishes wrinkles and lines and people can look younger. It saves them from cosmetic procedures because they can get similar results from cosmetics.”
While the skin looks better with every use, the effects do not always last long.“The effect of different Clinicians products is different. It depends on the product and usage. Some remain in place for a day, others for a week. However, regular usage of these products sometimes extends their effect to months,” revealed Saloni Chandramore, cosmetologist and director of Dr. Saloni’s Wellness Clinic in Mumbai.
While all third generation products are sought after, the most popular are those for lip enhancement and skin rejuvenation.“Microderma brasion cream is most popular as it is an at-home alternative to many peels and microderma procedures in clinics. It immediately rejuvenates, diminishes pigments and helps the skin glow,” informed Parasar.
Said Chandramore: “Clinicians lip enhancers are most in demand. The two other most popular products are microderma brasion and instant tightening serum.”
While the creams are targeted at anyone between 18 and 70 years of age, they cost anywhere between Rs.1,500 to Rs.4,000 and are available at major skin and dermal centres in the country.“Since the product is available only at clinics, it goes to the customers as per an expert’s prescription only,” Sheetal Badami, a Pune-based beauty and obesity consultant, told IANS.
Parasar, also director of Dubai-based cosmetic surgery chain Cocoona Centre for Aesthetic Transformation, said: “The products are sold only through clinics as we have products according to skin type for best results. “We have a range for oily skin, dry skin and normal skin. Also, one can discuss their requirements with a skin specialist so that the right product is suggested to them.”
Thanks to the instant results of the products, the showbiz industry, where celebrities usually opt for remedies like botox and cosmetic surgeries for a youthful look, is getting hooked to these.
“Bollywood and other celebrities do come to me for such treatments frequently. This helps them get the desired beauty enhancement as and when required, that too without any complex procedure,” revealed Chandramore.
Badami said: “For celebrities, every look and expression counts and with their busy schedules they don’t have time for long procedures and third generation products are a good solution for them.”
However, for confidentiality reasons, the experts refrained from revealing any names.Source
Friday, July 9, 2010
Twitter has decided to launch a Korean-language version' before the end of the year
" Twitter to launch Korean version before December "
SEOUL: Twitter has decided to launch a Korean-language version before the end of the year, according to a news report on Friday.
Sean Garrett, the company’s vice president of communications, told the Yonhap news agency that Twitter is planning to introduce a Korean language before December. Garrett has been in Japan and South Korea this week.
He said the Korean language is one of the company’s priority languages for introducing a translated version of Twitter.com as the number of Twitter users and traffic from South Korea has continued to grow.
Twitter was initially launched in 2006 as an English-language social networking and microblogging service that enables its users to send and read other user messages called tweets. It later launched translated versions in Spanish, Japanese, German, French, and Italian.
